
In the diagnosis of influenza, the test that boasts the highest accuracy is the PCR test (Real-Time RT-PCR). While the common rapid antigen test determines if a virus is currently in the body, the PCR test directly detects the virus’s genetic material, making its accuracy over 99.9%.
As of 2025, the PCR test is utilized as the “ultimate weapon” for cases where the result from a conventional rapid test is unclear, or for patients with a high risk of severe illness (such as the elderly and those with underlying health conditions).
Details of the Influenza PCR Test (2025 Japan)
| Item | Details |
| Formal Name | Real-Time RT-PCR (Reverse Transcription + Gene Amplification Test) |
| What it Detects | Influenza Type A and B (Plus subtyping is possible: H1N1pdm, H3N2, Victoria, Yamagata lineages, etc.) |
| Viruses Detected Simultaneously | Almost all mainstream kits for the 2024-2025 season test for Influenza + COVID-19 + RSV(3–4 items simultaneously). |
| Accuracy (Sensitivity/Specificity) | Sensitivity 99.5–100%, Specificity 100% (False negatives and false positives are virtually zero). |
| Time Required | Fastest equipment: 40–60 minutes / General hospital: 2–6 hours / Outsourced test: Morning of the next day |
| Specimen Collection Method | Nasopharyngeal swab (Swab deep into the nose) Note: Saliva PCR is not covered by insurance for influenza as of 2025. |
| Cost Estimate (30% Co-pay) | ¥1,800–¥3,500 (Varies based on the number of simultaneous tests) |
| Main Cases Covered by Insurance | Ages 65+ / Presence of underlying conditions / Pregnant women / High severity despite a negative rapid test / Need for hospitalization / Cluster outbreaks in facilities/schools / When deemed medically necessary by a doctor |
Main Locations for Receiving a PCR Test (As of 2025)
| Location | Time to Result | Key Features |
| Large General Hospitals/University Hospitals | 1–3 hours | Fastest. Available even at night. |
| Fever Clinics (PCR dedicated) | 1–4 hours | Often appointment-only. |
| Local PCR Centers | Same day to next day | Free or low-cost (depending on municipality). |
| Regular Clinics | Next day result | Slower due to outsourcing the test. |
Typical Patterns Where a Doctor Decides on “PCR”
- High fever and difficulty breathing persist after two negative rapid tests.
- High risk of severe illness, such as the elderly, diabetics, or those with heart disease.
- The entire family is positive, but the patient is rapid-test negative.
- Hospitalization is required (especially if a Tamiflu-resistant strain is suspected).
- When a school or facility requires knowledge of the “exact strain type.”
Summary
- Normal people get a rapid test first → PCR only if something is highly suspicious.
- PCR is the “ultimate weapon that provides a nearly 100% correct answer.”
- It is not used unless a doctor deems it necessary because it takes time and is more expensive.
At-Home Testing Kit Ranking (Combined COVID-19 and Influenza)
Here is the English translation of the ranking table for at-home diagnostic kits that test for both COVID-19 and Influenza A/B:
| Rank | Product Name (Manufacturer) | Targets Detected | Sensitivity (Detection Rate) (Estimate: 12-48h Post-Onset) | Result Time | Approximate Price (Per Test) | Suitability for Pregnant Women / Children | Key Features & Availability |
| 1 | Panbio COVID-19/Flu A&B | COVID + Flu A/B | COVID: Approx. 90% | Flu: Approx. 85% | 15 mins | ¥1,980 – ¥2,480 | ◎ (Shallow Nasal Swab) |
| 2 | クイックナビ-Flu+COVID | Same (COVID + Flu A/B) | COVID: 88% | Flu: 80–85% | 15–20 mins | ¥1,780 – ¥2,200 | ◎ (Designed for children’s use) |
| 3 | KBMラインチェック nCoV/Flu | Same (COVID + Flu A/B) | COVID: 85% | Flu: Approx. 80% | 15 mins | ¥1,480 – ¥1,980 | ◎ |
| 4 | イージードック Flu&COVID-19 | Same (COVID + Flu A/B) | COVID: 87% | Flu: 82% | 15 mins | ¥2,200 – ¥2,600 | ◎ (Many cases of use by pregnant women) |
