Influenza Vaccine Side Effects: How Long Do Pain and Fever Last? A Complete Guide Compared to the Benefits of Preventing Severe Illness

When getting the influenza vaccine, the most common concern is the “side effects,” particularly pain at the injection site and fever. Knowing the symptoms and duration of side effects beforehand can help you approach vaccination with peace of mind.

Based on actual 2025 data, nearly 80% of recipients experience “injection site pain,” but this usually subsides within 1 to 3 days. Systemic side effects (malaise, mild fever) occur in about 10% to 25% of people, but the duration is short (1 to 2 days) and is far milder than the high fever from actual influenza (39–40°C lasting 5 days).

Influenza Vaccine Side Effects: 2025 Latest Data Summary (MHLW + Clinical Practice)

SymptomFrequency (2024–2025 Season Actual Data)Peak TimeDurationManagement
Injection Site Pain60–80% (Most common)Immediately – Next day1–3 daysApply a cold compress + move the arm
Injection Site Redness/Swelling30–50%Next day – Day 22–5 daysApply a cold compress
Malaise/Fatigue10–25%Next day1–2 daysRest
Mild Fever (37°C range)5–15%6–24 hours post-shot1–2 daysMonitor
Fever ≥38∘C1–3%Next dayOnly 1 dayTylenol/Paracetamol is OK
Headache/Joint Pain5–10%Next day1–2 daysTylenol/Paracetamol
Anaphylaxis (Severe Allergy)1–2 per 1 million peopleWithin 30 minutes post-shotImmediateImmediate response at the clinic

Vaccine Type Side Effect Strength Ranking (2025)

RankVaccineEstimated Side Effect Strength
1st (Strongest)Fluad (High-Dose for Elderly)★★★★☆ (Stronger injection site reaction)
2ndRecombinant Vaccine (New)★★★☆☆ (Slightly stronger)
3rdStandard Domestic 4-Valent (Subcutaneous)★★☆☆☆ (Normal)
4th (Weakest)Intradermal Injection (Fine Needle)★☆☆☆☆ (Hardly any pain)

Side Effect Reality for Children (Under 13)

  • The second dose tends to result in fewer reactions than the first dose.
  • Approximately 5% to 8% of children develop a fever of ≥38∘C (lasting only 1 day).
  • Crying is mostly due to the pain of the injection itself, and 90% of children are energetic the next day.

Symptoms That “Absolutely Require a Hospital Visit” (2025)

  • Hives, difficulty breathing, or facial swelling within 30 minutes of vaccination → Immediately return to the clinic.
  • A fever of ≥39∘C persists for 2–3 days after the shot.
  • Joint or muscle pain so severe that you cannot walk persists for more than 3 days.

The Truth About Side Effects in One Sentence (2025)

“8 to 9 out of 10 people only experience ‘a sore arm + slight fatigue’.”

“Compared to the high fever of actual influenza (39–40°C keeping you in bed for 5 days), the side effects are less than 1/100th as severe.”

→ If you avoid the shot out of fear of side effects, you risk suffering 100 times more severely from the actual illness!

At-Home Testing Kit Ranking (Combined COVID-19 and Influenza)

Here is the English translation of the ranking table for at-home diagnostic kits that test for both COVID-19 and Influenza A/B:

RankProduct Name (Manufacturer)Targets DetectedSensitivity (Detection Rate) (Estimate: 12-48h Post-Onset)Result TimeApproximate Price (Per Test)Suitability for Pregnant Women / ChildrenKey Features & Availability
1Panbio COVID-19/Flu A&B COVID + Flu A/BCOVID: Approx. 90%Flu: Approx. 85%15 mins¥1,980 – ¥2,480◎ (Shallow Nasal Swab)
2クイックナビ-Flu+COVIDSame (COVID + Flu A/B)COVID: 88%Flu: 80–85%15–20 mins¥1,780 – ¥2,200◎ (Designed for children’s use)
3KBMラインチェック nCoV/Flu Same (COVID + Flu A/B)COVID: 85%Flu: Approx. 80%15 mins¥1,480 – ¥1,980
4イージードック Flu&COVID-19 Same (COVID + Flu A/B)COVID: 87%Flu: 82%15 mins¥2,200 – ¥2,600◎ (Many cases of use by pregnant women)